Fatigue is a physiological state which raises the risk of pathological changes in the organisms.

• A. True
• B. False
• C. Not sure
• D. Sometimes true

Answer: (A)

Fatigue is a physiological state that reduces the body's reserve to cope with stress and to maintain normal functions. When fatigued, attention, reaction time, and physiological regulation suffer, and processes such as immune response, tissue repair, and metabolic control can be impaired. This lowered reserve means the body is more susceptible to developing or accelerating pathological changes, especially with chronic or repeated fatigue. So the statement is true: fatigue raises the risk of pathological changes in the organism. If you’re unsure, options like not sure or sometimes true are less precise because fatigue generally increases risk rather than being unpredictable or only occasionally true.